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https://www.nist.gov/bioscience
Bioscience
Overview
NIST provides measurement assurance for the biotechnology industry through the development of quantitative analytical measurement tools for nucleic acids, proteins, metabolites, and cell systems to aid industry in the deployment of innovative biotechnologies and advanced biomaterials.
NIST standards and reference materials underpin advances in bioscience and biotechnology, contributing to human health and the U.S. economy.
NIST provides:
Quantitative measurements
Reference materials for quality control
Data for benchmarking
Leadership and technical advice for U.S. and international standards development efforts
We have specialized expertise in and equipment for measuring biological processes and systems, along with experience in managing the large amounts of data these measurements produce. Our work benefits:
Clinical medicine
The biopharmaceutical industry
Regulatory agencies
The DNA forensics community
The mass spectrometry community
The synthetic biology industry
Equipment manufacturers
The NIST Biofoundry
NIST Living Measurement Systems Foundry
The NIST Living Measurement Systems Foundry is enabling reliable, scalable, and safe engineering of cells that can sense and respond in controlled ways for applications such as living therapeutics, environmental remediation, and structured materials fabrication. This automated facility combines high throughput measurements and machine learning to create rapid design-build-test-learn cycles for cellular engineering. For more info: https://go.usa.gov/xmdkw
The NIST Genome Editing Consortium addresses the measurements and standards needed to increase confidence and lower the risk of using genome editing technologies in research and commercial products.
The NIST monoclonal antibody reference material — the NISTmAb — is used by biopharmaceutical firms for quality assurance and to evaluate new biomanufacturing methods and tools.
Facilities such as the NIST Center for Neutron Research help industry members develop the expertise to use rare neutron scattering tools. Leading biotech companies such as Genentech, Amgen, Regeneron and Pfizer are part of the nSoft consortium, using neutron science to explore protein-based pharmaceuticals produced by living cells.
The development of new platforms for characterization of complex microbial samples are hampered by lack of reproducibility and comparability across different
Consortium hosted by NIST dedicated to authoritative characterization of benchmark human genomes. Sign up for General GIAB and Analysis Team email lists
NIST is developing NMR-based metabolomics for use as a tool to expand research on the impacts of environmental stressors on marine organisms. The novel biology
We measured the levels of modified DNA bases following ү-irradiation of the halophilic archaeon, Halobacterium sp. str. NRC-1. In this first study to quantify
The NIST Genome Editing Consortium addresses the measurements and standards needed to increase confidence and lower the risk of utilizing genome editing technologies in research and commercial products.