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NIH Science in Seconds – Research News for week of March 20, 2023

Mar 27

Catch up on the latest #NIH research news on #COVID19, substance use disorders, and more:

youtube.com

NIH Science in Seconds – a weekly roundup of NIH’s research news. Read more about each of the featured news stories below. Week of March 20, 2023:1. A key im...

An #NIH-funded study suggests greater light exposure 3 hours before sleep during the 2nd trimester of pregnancy is associated w/ increased risk for gestational #diabetes. However, dimming lights and screens before bedtime may reduce this risk. bit.ly/3FImW1s

@nih_nhlbi

nhlbi.nih.gov

Greater light exposure prior to sleep may raise risk of gestational diabetes | NHLBI, NIH

With recognition for her outstanding public service, I announce the departure of

@CWolinetzNIH

from #NIH on May 6. I want to thank her for tireless dedication and contributions to NIH and the greater biomedical research enterprise.

Statement on Departure of Dr. Carrie Wolinetz

Dr. Wolinetz joined NIH in February 2015.

News: Buprenorphine initiation in the ER found safe and effective for individuals with opioid use disorder who use fentanyl

Buprenorphine initiation in the ER found safe and effective for

With historically high overdose death rates in U.S., multi-site NIH study reinforces importance of continued, uninterrupted access to addiction medication.

National Institute of Mental Health (NIMH)

@NIMHgov

Bipolar disorder is not the same as the typical ups and downs every kid goes through. The mood swings are more extreme and accompanied by changes in sleep, energy level, and the ability to think clearly. Know the signs and symptoms: nimh.nih.gov/health/publica #WorldBipolarDay

Infographic presents common signs and symptoms of bipolar disorder in teens and young adults. Link points to nimh.nih.gov/bipolardisorder

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National Institute of Mental Health (NIMH)

@NIMHgov

Digital Shareables on Bipolar Disorder

Today is #WorldBipolarDay. Help NIMH raise awareness about bipolar disorder by sharing informational materials based on the latest research. Share science. Share hope. #shareNIMH

nimh.nih.gov

Download and share informational graphics, social media messages, and videos, to help raise awareness about bipolar disorder.

Happy #NationalDoctorsDay to all the doctors and physicians in training who help keep us healthy today and every day.

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Artificial pancreas controls blood sugar in young children with type 1 diabetes dlvr.it/SlkDq4 #NIHResearchMatters

Artificial pancreas controls blood sugar in young children with type

Children aged 2 to 5 with type 1 diabetes who received an artificial pancreas had more stable blood glucose levels than those who received standard care.

#NIH has announced the winners of their

@ChallengeGov

#LongCOVID Computational Challenge. The 3 winners developed creative AI/ML models using EHR data to predict the likelihood of patients developing Long COVID. Congratulations!

linkedin.com

Announcing The NIH Long COVID Computational Challenge (L3C) Winners

In August 2022, the Rapid Acceleration of Diagnostics Radical (RADx®-rad) program at the National Institutes of Health (NIH) launched the Long COVID Computational Challenge (L3C) to support creative...

#NEI had the opportunity to host Congressman

@PeteSessions

yesterday on the

Bethesda campus. He met the

@NEIDirector

and visited NEI's senior investigator

@Kapilbharti123

's lab, where they talked about advances in #vision research.

@NEIDirector Michael Chiang and Congressman Pete Sessions.

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Congressman Pete Sessions and NEI Senior Investigator, Kapil Bharti.

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News: Increased use of telehealth services and medications for opioid use disorder during the COVID-19 pandemic associated with reduced risk for fatal overdose

Increased use of telehealth services and medications for opioid use

Study findings support the continuation of providing telehealth services for opioid use disorder and its related care.

In this interview from the early 2000s, Dr. Ruth Kirschstein, then director of

@NIGMS

, discussed how she advocated for women in science and equal opportunities for all individuals in the medical field. #WomensHistoryMonth

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NCI Center for Cancer Research

@NCIResearchCtr

@g_altanbonnet

and colleagues used a custom robotic platform and #ArtificialIntelligence to design a model that predicts how T cells will respond to different stimuli. The model could help design more effective cancer #immunotherapies #Milestones2023 #AI bit.ly/3yEblNa

National Cancer Institute

@theNCI

Mar 28

WATCH : To access the bloodstream 🩸 and travel to other parts of the body, cancer cells must pass through a portal made up of three cells. Understanding this process better may help researchers prevent cancer spread. ccr.cancer.gov/news/milestone #macrophage

@NCIResearchCtr

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📢 Our #ARPA-HDash is underway! 🏆 🏃‍♀️ Submit your idea TODAY through the online portal! polyplexus.com/healthdash

ARPA-H Dash tournament bracket abstract image

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News: FDA-approved drug shows promise in lab models for blinding childhood disease

FDA-approved drug shows promise in lab models for blinding childhood

Strategy may speed delivery of therapeutic options relative to time it would take to develop gene therapies.

Mixed-race woman potentially cured of HIV using stem cell transplant dlvr.it/Slg5g3 #NIHResearchMatters

Mixed-race woman potentially cured of HIV using stem cell transplant

A mixed-race woman with leukemia is likely cured of HIV after receiving a transplant including stem cells from banked umbilical cord blood.

Friendly reminder that if you have thoughts about the current state of postdoctoral research training and career progression within the biomedical research enterprise, the

would like to hear from you by April 14, 2023 📝💻bit.ly/3lDU2s0

National Institutes of Health Building 1

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#FraudAlert: HHS-OIG is alerting the public to a fraud scheme that uses social media and fake websites to steal money from individuals by offering fake HHS grants. Read more: bit.ly/3yf3w0d.

GIF

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Mar 28

NIH Research: Complete wiring map of the insect brain dlvr.it/SlcY7g #NIHResearchMatters

Complete wiring map of the insect brain

The first complete wiring map of the larval fruit fly brain could aid future brain research and inspire new machine learning architectures.

There’s a disproportionate burden of pain among veterans/service members.

@NIH_NCCIH

-led Pain Management Collaboratory explores nondrug approaches by looking through the lens of whole person health.

@painmc3

#NIH

directorsblog.nih.gov

A Whole Person Approach to Lifting the Burden of Chronic Pain Among Service Members and Veterans

Chronic pain and its companion crisis of opioid misuse have taken a terrible toll on Americans. But the impact has been even greater on U.S. service members and veterans, who often deal with the co…

Scientists at #NIH-funded

@UCSF

have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor. The findings get researchers a step closer in understanding the sense of smell.

ucsf.edu

Making Sense of Scents

In a first, UCSF scientists created a molecular-level, 3D picture of how an odor molecule activates a human odorant receptor.

As part of

’s UNITE initiative, we’re pleased to share a new funding opportunity: Instrumentation Grant Program for Resource-Limited Institutions. Interested applicants are invited to attend a webinar on Wed., 5/3, 3-4:30 p.m. ET. #NIGMSFeedbackLoop bit.ly/3LVaMGz

Promotion of the NIGMS Feedback Loop blog. Text reads: Funding Opportunity: Instrumentation Grant Program for Resource-Limited Institutions (S10)

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Mar 28

News: NIH researchers discover new autoinflammatory disease, suggest target for potential treatments

NIH researchers discover new autoinflammatory disease, suggest target

The disease is caused by mutations in the LYN gene, an important regulator of immune responses in health and disease.

Michael F. Chiang, MD

@NEIDirector

Mar 27

To high school students: we want YOU to enter

@NatEyeInstitute

’s #EyeOnTheFuture teen video contest! Winners get $2,000 and a free trip to

. See this video and follow 3 easy steps... bit.ly/3lGhky2

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Women scientists have made invaluable contributions to #NIH_IRP research throughout

history. In celebration of #WomensHistoryMonth, we are spotlighting some of the women scientists who have been at the forefront of science and administration at NIH: bit.ly/40GlEvQ

Mar 27

News: HIV can persist for years in myeloid cells of people on antiretroviral therapy

HIV can persist for years in myeloid cells of people on

NIH-funded study confirms white blood cell subtype as HIV reservoir, suggests new target for cure efforts.

Scientists complete first map of an insect brain

Mar 24

#NIH had the opportunity to host Dr. Ashish Jha,

@WHCOVIDResponse

coordinator, on the NIH Bethesda campus. He visited the

@NIAIDNews

Vaccine Research Center and

@NIHClinicalCntr

and heard about neutrophils in autoimmune disorders from an

@NIH_NIAMS

postbac.

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#TissueChips took flight to

@ISS_CASIS

for the last time! As part of the NCATS-led Tissue #ChipsInSpace program, nine projects were sent to space to study diseases & conditions related to the effects of aging. Learn more about the program and what’s next: bit.ly/40fC8eF

Astronaut in space assists with kidney tissue chips.

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#TUBERCULOSIS NEWS: On March 24, #WorldTBDay, NIAID reaffirms its commitment to #EndTB through new and better diagnostics, treatments, and vaccines. Learn more: bit.ly/3GcLwrJ

Scanning electron micrograph of Mycobacterium tuberculosis particles (colorized orange), the bacterium which causes TB.

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Researchers have completed the most advanced brain map to date of a larval fruit fly. The detailed diagram traces every neural connection in the larval fruit fly brain, which is similar to human brain structure and is a commonly used scientific model. bit.ly/3FoYX7p #NIH

hub.jhu.edu

Researchers from Hopkins and Cambridge map the brain of a baby fruit fly, a landmark achievement that brings scientists closer to true understanding of the mechanism of thought

National Library of Medicine

@NLM_NIH

Mar 23

Need a dog-tor for #NationalPuppyDay? 🐶🩺 Produced by Defrahn Studios (Sayre, PA) between 1950 and 1970, this postcard from the NLM Zwerdling collection features two adorable puppies posing as doctor and patient. View in the NLM Digital Collections: loom.ly/71_ne1A

Postcard featuring a color photograph of two Siberian husky puppies. The husky on the left is wearing a toy stethoscope around its neck as if it were a nurse or a doctor. The husky on the right is laying in a basket with its tongue sticking out. On the side of the basket is a small card that reads, "health chart".

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An enzyme found in the malaria parasite may be a promising target for new antimalarial drugs. Compounds called thienopyrimidines could target this enzyme to kill the Plasmodium falciparum malaria parasite at multiple life cycle stages. bit.ly/42pG5PA #NIH

science.org

Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Evolved resistant clones and biochemical assays identify and validate Plasmodium falciparum cIRS as a promising target.

NIH Office of Portfolio Analysis

@NIH_OPA

Mar 23

#ThrowbackThursday when

developed the CRISP (Computer Retrieval of Information on Scientific Projects) database in the 1980s! Users could look up NIH funding for specific investigators & search abstracts of funded projects. 📷

@historyatnih

📁tinyurl.com/3fe4t6wr

Black and white photo of a man writing in a notebook and sitting in front of a computer. He is using the computer database CRISP.

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Mar 22

News: NIH study reveals shared genetic markers underlying substance use disorders

NIH study reveals shared genetic markers underlying substance use

Breakthrough findings could lead to more effective prevention and treatment strategies for multiple substance use disorders.

Nature Reviews Bioengineering

@natrevbioeng

Mar 22

The

has established a new Center for Biomedical Engineering Technology Acceleration. We talked to the Center’s Director Manu Platt about their plans and the focus on diversity, equity, inclusion and accessibility

@DrPlattLab

@NIBIBgov

go.nature.com/3TOP7BT

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The #nihHEALinitiative envisions a world with: ➡️Safe & effective ways to treat chronic pain ➡️Prevention services for people going through difficult life transitions ➡️Knowledge & tools to help people become and stay healthy in recovery Learn more: bit.ly/3kHDWNV

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