The Accelerating Medicines Partnership® (AMP®)
Heart Failure (HF) is an innovative new project that
uses next-generation phenomics to define heart failure
subtypes and treatment targets
The Accelerating Medicines
Partnership® (AMP®) Heart
Failure (HF)
Read MoreAMP HF

Important Updates

AMP® HF Inaugural Meeting

The Accelerating Medicines Partnership® (AMP®) Program in Heart Failure (HF) Inaugural Meeting will be held on September 29, 2022 at the Gaylord National Resort and Convention Center in National Harbor, Maryland.

The AMP HF Program, a public-private partnership facilitated by the FNIH, will advance our understanding of heart failure with preserved ejection fraction using two complementary and integrated research components: analyzing existing HFpEF datasets, sourced from public and private sector funded studies, and initiating a new clinical trial to confirm retrospective findings in an observational cohort with a goal to develop a framework for new precision treatments.

2022-23 Research Skills Trainees

The HeartShare Research Skills Program trainees for the 2022-2023 academic year have been announced. They have started their 3-month bootcamp to receive hands-on training in data management, programming, and application of machine learning and artificial intelligence approaches to clinical research in data science. They will spend the remaining 9 months in the program to complete a mentored research project related to HFpEF, using the approaches they learned in the data science bootcamp.

For more information about the program and to meet the trainees visit the “Research Skills Program” page or click the link below.

Latest News

Nature Reviews Drug Discovery – AMP HF

FNIH AMP® HF Launch Announcement

AMP HF Inaugural Meeting

AMP HF Launch Meeting Important Links

Follow a manual added linkFollow a manual added linkLink to: AMP Heart Failure Launch

Study Sites

The AMP HF Study consists of a data translation center and 6 clinical research centers.

FAQ

If you or a family member has been invited to participate in this study, you may have questions. Review our frequently asked questions to get the answers you are looking for or contact us for more information.

Study Design

The AMP HF Study is an innovative multi-center study of HFpEF, funded by NHLBI to define HFpEF subtypes and treatment targets.

HeartShare is comprised of retrospective and prospective components.

The HeartShare Retrospective study will aggregate and harmonize data from previously completed cohort studies and trials. The phenotype data will be combined with an image repository and additional omics assays.

The HeartShare Deep Phenotyping Study is composed of 2 prospective, multicenter, longitudinal components: (1) the HeartShare Registry and (2) the HeartShare Deep Phenotyping Cohort study involving up to 10,000 and 2,000 participants, respectively, enrolled from at least 6 HeartShare Clinical Centers.

Retrospective and Prospective Data

Multiple data types will be harmonized.

Existing data sets from cohort studies and trials, including images and omics analyses, will be aggregated and harmonized to establish the retrospective data.

Details of what cohort studies and trials will be in the retrospective data will be available soon.

Prospective data will generated from the registry and deep phenotyping study cohorts.  Both cohorts will have baseline and longitudinal data.  (ADD MORE DETAILS ABOUT THE DEEP PHENOTYPING COHORT)

To learn more about the prospective data:

Get Involved

Contribute data or apply for access to the data or establish an ancillary study in AMP HF

Helpful links for details and information about how you can get involved or collaborate with AMP HF:

Data Sharing / BioData Catalyst

Research Skills Program

Publication and Ancillary Study Proposal

For more information, contact us.

The Accelerating Medicines Partnership® (AMP®) Heart Failure (HF) Program - HeartShare