Office of Research & Development |
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Project Number: | I21RX003340-01A1 |
Title: | Long-term effects of opioid use in a mouse model of repetitive mild traumatic brain injury |
Principal Investigator: | Benoit Mouzon |
Location: | Tampa, FL |
Congressional District Code: | 14 |
Research Service: | Rehabilitation R&D; |
Project Period: | August 2020 - July 2022 |
FY 2021 Funding Amount: | $99,943 |
Total Award Amount (all years): |
$199,925 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Individuals who have sustained a traumatic brain injury (TBI) are at a higher risk for substance use disorders, and while clinicians and researchers widely acknowledge issues with opioid abuse and dependence, pre- clinical investigations have published data suggesting positive benefits of opioids as a potential therapeutic strategy for patients of TBI. However, concerns regarding the effect of opioid exposure on neuronal degeneration have also emerged in both pre-clinical and clinical settings.... |