Office of Research & Development |
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Project Number: | I01BX004232-01A2 |
Title: | Intra-renal T-cell heterogeneity in ADPKD patients |
Principal Investigator: | Michal Mrug |
Location: | Birmingham, AL |
Congressional District Code: | 7 |
Research Service: | Biomedical Laboratory R&D; |
Project Period: | October 2019 - September 2023 |
FY 2021 Funding Amount: | $156,800 |
Total Award Amount (all years): |
$709,800 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: PROJECT SUMMARY/ABSTRACT Chronic kidney diseases (CKD) are among the most significant public health problems with an aggregate prevalence of ~15% and virtually no curative therapies. The most promising group of disorders that may allow identification of urgently needed CKD drug targets are those with a known underlying molecular defect. Among them, the most prevalent and most commonly leading to end-stage renal disease (ESRD) is autosomal dominant polycystic kidney disease (ADPKD; 600,000 patien... |