Eric TopolVerified account

@EricTopol

physician-scientist, author, editor

La Jolla, CA
scripps.edu/translational
Joined November 2009
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  1. Pinned Tweet
    28 Nov 2020

    This will go down in history as one of science and medical research's greatest achievements. Perhaps the most impressive. I put together a preliminary timeline of some key milestones to show how several years of work were compressed into months.

    1,146 replies 10,265 retweets 35,146 likes
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  2. 2 hours ago

    "Mask-wearing at the heart of the great British Covid divide" Sounds familiar.

    24 replies 108 retweets 320 likes
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  3. 5 hours ago

    A case series of 3 teens with recent Covid who presented and were hospitalized with neuropsychiatric symptoms and found to have antibodies in their cerebrospinal fluid by and colleagues

    20 replies 222 retweets 401 likes
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  4. 5 hours ago

    One year after mRNA (Moderna) vaccination, memory B cells kick in to protect against Covid pneumonia, but there is a brief delay that sets up the opportunity for lung disease to occur. Delta challenge in the macaque model by and colleagues

    11 replies 73 retweets 215 likes
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  5. 5 hours ago

    Just published Covid community transmission was occurring in Europe and the US in January 2020 and only 1-3% of cases were getting detected in March; international travel a key driver

    27 replies 208 retweets 450 likes
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  6. 6 hours ago

    Pockets of very high vulnerability In San Diego County (2nd largest in California) there are many spots with very low vaccination rates , representative of across the US

    17 replies 42 retweets 117 likes
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  7. 7 hours ago

    Human devolution :-) by

    14 replies 95 retweets 315 likes
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  8. 18 hours ago

    Can digital technologies improve health? A new 50-page report commissioned by and , with particular attention to reducing inequities

    9 replies 215 retweets 507 likes
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  9. Oct 24

    The Delta variant sub-lineage AY.4.2, also known as "Delta plus," has aroused concern with its sequence found in ~10% of recent UK cases. Here are the mutation maps of both, notable for minimal difference at 2 sites (red arrows)

    22 replies 221 retweets 562 likes
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  10. Oct 24

    Japan fully contained after its worst surge related to Delta, 💉 quickly rose to now 78% of total population w/ ≥ 1 dose, test positivity went from 25% to 1%, cases >23,000 to <400. Everything is open, no restrictions except use of masks. The mood is celebratory It can be done.

    209 replies 1,491 retweets 5,626 likes
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  11. Oct 23

    Features of among >157,000 adults and children with Covid infections with matched controls Lower absolute incidence in children and teens but impact statistically significant across all age groups

    23 replies 235 retweets 505 likes
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  12. Oct 23

    What happens when teens are not vaccinated

    262 replies 2,939 retweets 6,919 likes
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  13. Oct 23

    Just out "Uncomfortable Truths — What Covid-19 Has Revealed about Chronic-Disease Care in America" and what to do about it by

    22 replies 103 retweets 364 likes
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  14. Retweeted
    Oct 22

    This is the best news we've had in a while. 3rd dose is our next weapon against this virus, and it's a great one 🤺 . It will help to keep case numbers low in highly vaxxed populations, and protect the vaccinated even in places where this fails! Can't wait to get mine! 💉💉💉

    The 1st randomized trial of a booster (3rd) shot in 10,000 people, placebo-controlled, shows 95.6% efficacy, with 5 cases (Pfizer vaccine) vs 109 in placebo group, Delta variant, broad benefit across age groups
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    44 replies 144 retweets 691 likes
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  15. Oct 22

    A prospective study before vaccination shows frontline and essential workers have a higher risk of Covid infections than health care personnel (yet they are far less vaccinated)

    11 replies 87 retweets 211 likes
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  16. Oct 22

    From the commentary on this review

    7 replies 45 retweets 127 likes
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  17. Oct 22

    After almost 2 years of Covid, the overwhelming fixation on hospitalizations and deaths as the only important outcomes for getting infected is untenable. Deliberately ignoring and its functional impairment will not make it go away.

    80 replies 1,036 retweets 2,981 likes
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  18. Oct 22

    The latest from the UK on AY.4.2 ("Delta plus"), 6% of cases in past week, designated a variant under investigation (which is below variant of interest or concern categories)

    18 replies 115 retweets 256 likes
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  19. Oct 22

    An assessment of Covid's impact on cognitive function in 740 individuals finds "a relatively high frequency of cognitive impairment several months after patients contracted COVID-19"

    54 replies 930 retweets 1,739 likes
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  20. Oct 22

    Here's the event curve from the FDA briefing documents

    3 replies 25 retweets 99 likes
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  21. Oct 22

    In over 2200 children ages 5-11, a placebo-controlled trial of a dose of 10 μg, 1/3 of adults, showed 90.7% efficacy of Pfizer's vaccine (3 cases in vaccine, 16 in placebo)

    45 replies 227 retweets 718 likes
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