Researchers have created an atlas representing changes in the levels of RNA made in different cell types in the ear following noise-induced hearing loss. They also discovered certain FDA-approved medications for diabetes and other disorders may protect against noise-related hearing loss.
Neurturin, a muscle-produced protein, improves muscular metabolism, motor coordination, and exercise performance in mouse models. The discovery could have implications for treating ALS and other disorders associated with neurological disorders that affect muscles.
Researchers identified key alterations in gene expression and structure of the developing human brain that makes it unique among other animal species.
Researchers highlight some of the current strategies being pursued to help restore lost function and regenerate brain areas affected by Parkinson's disease.
Drugs that increase signaling of Sonic Hedgehog (Shh) can help suppress the involuntary movements associated with dopamine replacement therapy for those with Parkinson's disease.
A newly identified gene therapy pathway has the potential to protect us against dementia and cancer, researchers report.
Stem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.
Male children with isolated GnRH deficiency (IGD), a rare endocrine disorder associated with a lack of sex hormone during the second trimester of development, report more gender non-conformity than males without IGD. The same was not true for females with IGD.
People with ADHD had a 34% higher risk of developing dementia than those without the disorder. The risk of being diagnosed with Alzheimer's, the most common type of dementia, was 55% higher for those with ADHD.
Researchers have identified 2,000 genes in humans linked to longevity. The genes are associated with biological mechanisms that drive the prolongation of life in mammals, including DNA repair, coagulation, and immune response.
A new study on aging reveals a surprising discovery about the connection between protein shape and mitochondrial health.
A new, open access repository incorporates frequently asked questions and answers by genomics researchers to provide a better general understanding of what their studies do, and do not show.