• Keratoplasty — the last option to “fix” the eyes if everything is bad (and something about modern methods)

    • Translation

    Nylon 10/0 (to sew the cornea)

    For the “last chance” operation or cornea transplant, donor tissue is needed. Specifically, we are interested in tissue with a thickness of 500–600 microns for penetrating keratoplasty. Next you need to work with this film with your hands, sew with a thin nylon thread. Then, when the cornea grows together, remove the suture. No biodegradable materials — their decay products will begin to lysing and can cause inflammation, which will exclude a positive result of the operation. Moreover, the transplant is recommended to flash twice around the perimeter — this increases the chances of its correct and uniform fixation. The second layer of nylon is most often not removed at all, because as long as it does not interfere, we don’t touch it.

    But let's start from the beginning. Specifically, from situations where a person may need this difficult for Russia operation, but quite familiar in Germany. It is of three types:

    • PKP, that is, the removal of the entire cornea of ​​the patient, for example, with a diameter of 7 to 8.5 mm and sewing on a new one.
    • DALK, that is, corneal tissue transplantation with the exception of the Descemet's membrane and endothelium.
    • DMEK, that is, the «installation» of only the layer of the Descemet's membrane and endothelial cells instead of the same layer in a patient.
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  • How do doctors do the vision correction themselves

    • Translation


    Of course, “we cannot do it ourselves” —the surgery requires another surgeon whom you trust 100%. Answering the question of who the relatives trust — I use mine myself. I did the operation to my mother, aunt, daughter, husband — who needed something “to fix”. Walter operated on his wife and father-in-law.

    We can usually do this while shooting or tell how it happens, with the consent of loved ones. We do this when we need to “sacrifice” someone for the sake of science. In our clinic already 6 people after laser vision correction. In the network of clinics SMILE EYES also a few people. The last case — we have 7 years of work in the position of operating nurse-administrator girl Anya, she meets and escorts patients for refractive operations. She is experienced with experience: by the age of 35, fifteen she wore soft contact lenses, sometimes she used glasses. The idea of ​​correction lived in her for all 7 years — as it happens, she saw many times in the form of records from the operating rooms. She saw both Lasik and femtoLasik, and only the operation of vision correction ReLEX SMILE (minimally invasive lenticle extraction) instilled in her confidence in safety and painlessness.

    About Anya: I was preparing for the operation as it should be — for a week I honestly took off contact lenses and used glasses. The patients of the clinic were surprised and asked why she was wearing glasses, explaining that she was preparing for a correction. The day was chosen so that she spent the morning in the clinic; in the afternoon, a correction could be made. On this day, I had several SMILE, several SMILE operations — with Walter, who came from Germany. We agreed that Anya will be operated by Professor Sekundo, and I will help camera operators with shooting.
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  • We implant an artificial lens (you will need it after 60 years)

    • Translation


    The lens in your eye can change its optical power: when you focus somewhere on the vision, this is what happens. Payback for the «moving parts of the mechanism» — wear with age. At about 40-45 years old, problems usually begin with age-related visual impairment; in 60-70 years, you need up to three pairs of different points. At the same time, the clarity of view is reduced due to the process of sclerosis and lens opacity — it is worth thinking about replacing the lens, until it becomes dim and becomes completely rigid.

    To date, the technology of replacing the lens is standardized and well developed. Potential risks are generally somewhat higher than with laser vision correction, but at present this type of surgery is performed even on transparent lenses with refractive purpose (when the patient does not like to wear glasses with thick glasses), that is, it is quite a “household” task for ophthalmology.
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  • Top 10 IoT Healthcare Solution Providers You Can Trust in 2020

      The role of IoT in the healthcare industry has been transformed by top IoT healthcare solution providers. IoT healthcare companies have created a path for new innovation, smarter systems and digital healthcare solutions.

      As stated by the Market Insights Reports,The global IoT in healthcare market was valued at $55.5 billion in 2019.The report also suggested that the market would grow at a CAGR of over 25% during the forecast period of 2019 to 2026. Moreover, with the current global pandemic of COVID-19, top healthcare IoT companies are vying opportunities to further this growth and invent newer IoT healthcare solutions.

      image

      In this article, we take a look at the top 10 IoT healthcare solution providers. These top healthcare IoT companies endorse smart healthcare solutions such as remote patient monitoring systems, IoT healthcare apps and other digital healthcare solutions. These inventions attain an exceptional opportunity to improve the quality of treatments, which eventually will improve the health of the patients.

      So, here are the new-age innovators of the healthcare industry – The Top 10 IoT Healthcare Companies:


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    • Cataract: it is waiting for you personally (if you live, of course)

      • Translation

      This is a model of an intraocular multifocal lens from Carl Zeiss. The real size of such a lens is 11 millimeters, the diameter of the optical zone is 6 mm.

      The cataract is, simplifying, age opacification and consolidation of a crystalline lens. According to the classical definition, we are talking about the turbidity of any type. First, something gets in the field of view, a general “fog” appears, you want to wipe dirty glasses, then you do not see the letters in the book, then you want to turn on the light brighter or, on the contrary, you hide from the bright light, and then wake up one fine morning and understand that you can not find slippers. And you see nothing at all — only the shadows. This process sometimes stretches for many years, but slippers are still lost. Mention of clouding that develops in the eyeball, there are still thousands of years before our era.

      The treatment procedure has historically been very peculiar — reclination of a cloudy lens. The doctor took the patient with a very dense lens — to that dense stage that the patient is already blind. During the excavations of the settlements of ancient Greece and Rome, the tools used by doctors to remove cataracts were found — sharp needles that pierced the eye and lens, destroying its supporting apparatus. The lens could come off and, by virtue of its gravity, could also fall down from hitting the back of the head with a heavy stick several times. Sometimes the patient died during the emergency eye care, sometimes he had a concussion, and sometimes the lens fell off the ligaments and flew deep into the eye. The patient began to see again — he had a huge lump and vision of about +10 +15 diopters.

      Now two news. The bad — people began to live to cataracts more often, and it is inevitable. Good — we have something better than sharp needles and a heavy stick.
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    • The QC House of Cards

        There’s Gold in Them Thar Hills

        Gold rushes can make people crazy. 1848 was enough of an indicator of that. When Sam Brannan announced to the world: ‘Gold! Gold! Gold from the American River!’, half the world’s population (or so it seemed to the tiny California population which lived there at the time) descended on the soon to be the newest state of the union.

        San Francisco, before a small hamlet with a few hundred pioneers living there, became a centre of vice, murder and debauchery overnight.

        image

        Two hundred years before tulip mania hit Europe, and like in California with its argonauts or 49ers, it impoverished more than it made rich. In the early 2000s, too, the Dot.Com bubble created a speculative tendency in people when irrationality took over all reason.
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      • AdBlock has stolen the banner, but banners are not teeth — they will be back

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      • From four to thirty two. Early years of computers and networks in Russia

          Part I: From four to eight



          I like to read the memoirs of people who observed the computers taking first steps in their countries. They always have something romantic about them. Usually, such memories are greatly influenced by the circumstances of that encounter with his first computer: it could be the workplace, or education establishment, it could be just an unexpected and random thing.

          Like many of my friends, I was lucky to see the end of that special romantic period, when computer makers were not trying to please the regular users. They were creating the devices with distinctive and unique features they thought were right for some of reasons. This approach is clear to see in both software and hardware. Such features were making the device to sell in millions or be a commercial failure.

          It all started differently for different people. Some of them were working with buzzing massive computers that could fill an entire room, the others had desktop-style home computers. There were people, who made their first computer themselves using specialist magazine publications. Different types of computers created the variety of specific traditions, interests and subcultures.
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        • IT specialist's vision: what you personally need to know

          • Translation


          — Which is better: glasses, lenses or laser vision correction?
          It is best to see without any means of correction. If you are completely satisfied with the glasses — keep calm, no other correction is needed. Lenses — this method of correction requires adherence to clear rules of use, which is ultimately more costly and risky, but it is very popular because the main dangers do not appear immediately after the start of wearing, but years later.

          — I decided to stay on the glasses, but I am afraid that the car's pillow will open in my face and they will become contact lenses. What to do?
          In my surgical experience, modern airbags do not injure eyeglasses. Eyes and face are usually damaged by windshield fragments. If you are concerned about the safety of glasses, then think about the modern, with polycarbonate lenses, they are incredibly durable, the car drives on crash tests.

          — Is it true that all eye disease from the computer?
          No, it's not true. The main cause of problems with optics — myopia, hyperopia or astigmatism — is genetics. Adverse environmental conditions, especially during long-term work at close range, are important in childhood, when the development of the organism is not yet complete. And such diseases as cataract, glaucoma, retinal detachment and other diseases occur with the same frequency in those who work at the computer for hours and in those who do not know where the computer has a power button.
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        • New lunar landers to be created with the help of additive manufacturing

            image

            The USA's National Aeronautics and Space Administration (NASA) has chosen three private companies to participate in the development of landing modules for the new Artemis lunar program. Among them are two enterprises that widely use 3D printing technologies in the production of rocket engines — Jeff Bezos' Blue Origin and Elon Musk's SpaceX. NASA seems to approach the matter carefully and generously, financing the development of lunar manned vehicles in three competing directions at once.
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          • «Augmentation» eyes: what do we build into it today, and what else will remain under it

            • Translation

            In surgery, the term «augmentation» is used for a specific type of intervention, for example, hardening (building) the skeleton of an organ. We will talk about the empowerment of biological vision at the expense of implants.

            You can not just take out a piece of tissue from the eye, as during laser correction, but also insert something new there. For example, an implant that allows you to see at night. Or DVR. Or — what is being done now — just an internal contact lens made from a biocompatible polymer.

            Therefore, when you read about new opportunities for contact lenses, remember — all this can be built into a person. Of the most promising technologies — transfer images from your eyes to a computer and vice versa. If you are lucky, in 10 years you will be able to search for a given word in a paper book, as you are now looking for on a web page.

            But let's still go back to the real world and talk about phakic lisch, corrective vision for those who can not help the laser.
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          • Guide for entrepreneurs to launch an on-demand grocery delivery app amid the coronavirus pandemic



              After the onset of the coronavirus pandemic, Instacart, a popular online grocery platform, hired 300,000 workers to meet the demands of the people. In addition, they are planning to hire 250,000 more. Such is the demand for online grocery platforms nowadays. People are in self-isolation with restricted outdoor movements. The fear of contracting the disease is so high that people are looking for alternative ways even to access essential services. As a result, smartphone applications are gaining increased attention from people all over the world.
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            • FAQ about laser correction ReLEx SMILE: yes, in Russia there is, but no, in Russia there isn’t

              • Translation


              — Are small-invasive laser vision correction operations done in Russia using the Small Incision Lenticule Extraction method?

              Yes, about 10 years already. Every year, more and more at conferences of ophthalmologists, questions arise not at the level of “What is this?”, But at specific practical nuances of technology. VisuMax lasers exist in several clinics in Russia, but it is much less used under ReLEx SMILE than under femtoLASIK. Historically, it happened in Russia that this technology is little used in the central part and is actively used beyond the Urals.

              — What is the story with licenses for specific operations?

              Zeiss sells cones with licenses. A cone — a replacement part adjacent to the eye — is purchased with a license to use a laser procedure, usually in batches of 10 or 100 operations. For example, 10 cones and 10 licenses are received. Licenses are driven through the laser menu, and it allows you to use the appropriate cones for the appropriate program types. Licenses for SMILE separately, for femtoLASIK separately, for FLEX, rings and additional corrections are also separate licenses. Most manufacturers of femtosecond and some excimer lasers have a similar situation. Licenses for excimer operations are not needed, perhaps, except on models of about 5 years old and older.

              — And you can not get such a license for SMILE?

              Easily. Firstly, this module in the laser is as an expensive option, so the device itself without the SMILE option is cheaper. Secondly, if this option is available, then licenses to carry out the operation ReLEx SMILE can be acquired only after conducting 5–10 test runs on pig eyes, then performing at least 10 femtoLASIK operations on patients, then 50 FLEX operations, and only after that Buy a SMILE license for a specific surgeon.
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            • A couple more unobvious things that you might not be told before laser vision correction

              • Translation

              Today, without the «tin», as you asked

              There is already a post about how the laser cuts by creating millions of cavitation bubbles in the cornea layer of the eye, and analyzing telemetry from the real operation in seconds with comments of the surgeon's actions.

              Now FAQ about various related things


              — If I look away while the laser is running, what will happen?

              You simply will not work. In fact, immediately after anesthesia, the eye is pressed against a special pneumocapture. To blink at you too will not leave because of fixing (it is not long and not for long). The only moment where it is possible to seriously disrupt the course of the operation is to pull the head down strongly, pulling it out of the headrest by a serious willed effort. In this case, the operation will instantly stop. More precisely, it will stop even before the loss of capture (details below).

              — How should an operating room be prepared?

              In general — as a normal operating room, that is, a room with a clean area (air filtration, overpressure to prevent contamination from the outside after cleaning). It is important for the procedure that microparticles of dust flying in the air do not fall between the laser lens and the eye.
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            • Four Ways Quantum Computing Will Change Artificial Intelligence Forever

                If science were a dating app, quantum physics and machine learning probably wouldn’t be a match. They’re from completely different fields and often require completely different backgrounds and skills. But, throw in a little quantum computing and, suddenly, that science-matchmaking app becomes Tinder and the attraction between the two is palpable.

                image

                (Credit: cmo.adobe.com/articles/2017/5/how-will-artificial-intelligence-impact-business-tlp-ptr.html#gs.5zlifl)

                Even though the extent of change that quantum computing will unleash on AI is up for debate, many experts now more than suspect that quantum computing will definitely alter AI at some level. Analysts from bank holding company BBVA, for example, point toward the natural synergy between quantum computing and AI as reasons why quantum machine learning will eventually best classical machine learning.

                “Quantum machine learning can be more efficient than classic machine learning, at least for certain models that are intrinsically hard to learn using conventional computers,” says Samuel Fernández Lorenzo, a quantum algorithm researcher who collaborates with BBVA’s New Digital Businesses area. “We still have to find out to what extent do these models appear in practical applications.”
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              • Laser telemetry for vision correction: a complete operation with comments (not for the faint of heart)

                • Translation
                Now I will show what doctors usually never show to patients. More precisely, it shows everything in the form of a beautiful render, from which it does not follow at all that a piece of metal will stick up in your cornea for a couple of minutes. Fortunately, you will not feel this because of the anesthetic premedication, you will not know and do not remember, because the piece of iron will be out of focus.



                So, watch the video, and I will show the frames with comments. This is a real operation on a patient in a German clinic, the recording was made on a device like the “black box” of the VisuMAX device. In this case, the patient has agreed to use the recording for training purposes, usually access to such records is strictly limited.
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              • Laser that cuts inside the cornea: ReLEx procedure at the physical level

                • Translation
                The idea — to take and cut a lens in a transparent cornea — is not new. At first it was done manually, with a scalpel directly on the surface (difficult and very rough, with a sea of side effects). The first laser was used in 1979, then it was a pulsed infrared emitter with an effective pulse length of 4 nanoseconds.


                Step 1: creating a plasma bubble, in fact — a microburst. Step 2: expansion of the shock and heat waves. Step 3: cavitation bubble (plasma expansion). Step 4: the formation of a parallel slice at the expense of several adjacent laser focus points.

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              • Agile English teaching. What is it?



                  Modern-day agile English teaching has come to take the place of rigid, cut-and-dried lessons that are fast becoming a thing of the past.

                  Let me clarify what I mean by agile teaching that is bound to substitute conventional teaching.

                  Some decades ago and up until recently it was perfectly valid to choose a certain textbook and go through it module by module together with your students (be it a group or individual learners). Given the abundance of high-quality materials readily accessible online and offline, it is completely unthinkable to proceed with this outdated approach.
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                • Why I keep track of spendings in a personal app made with Git+JS

                  • Translation

                  Hi, folks, let me share my experience of creating an application to keep track of my spendings. Specifically, let me do it by answering the following questions:


                  1. Why keep track of spendings in an application?
                  2. Why did I create the application as a personal project?
                  3. Why does the project use Git+JS?

                  1. Why keep track of spendings in an application?


                  I, like many people out there, wanted to become rich and successful. To become rich, one is often advised to run a personal budget, that's what I started to do several years ago. I'd like to point out that running my personal budget hasn't made me rich and successful, and I increased income simply by moving to Moscow.

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